Cell division regulator, S. pneumoniae gpsb, in complex with peptide fragment of penicillin binding protein PBP2A

Structure

x-ray diffraction · 3 distinct chains · 55% helix, 7% strand (DSSP).

Ligands and binding sites

• NI · Nickel (II) ion · metal · chains A, B
• SO4 · Sulfate ion · ion · 6 copies · chains A, G, B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

5 interfaces between chains.

• A–B · 2206 Ų buried · 31 hydrogen bonds · protein-protein
• B–C · 519 Ų buried · 12 hydrogen bonds · protein-protein
• A–G · 442 Ų buried · 13 hydrogen bonds · protein-protein
• A–C · 52 Ų buried · 1 hydrogen bond · protein-protein
• B–G · 30 Ų buried · 0 hydrogen bonds · protein-protein

Compared structures

• 6GQN · Cell division regulator, S. pneumoniae GpsB, in complex with peptide fragment of… · the same entry in another collection · chain A against A, TM-score 1.00
• Q8DR57 · AlphaFold monomer V2.0 prediction for cell cycle protein gpsb (Q8DR57) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q8DR57
• Elsewhere: RCSB PDB 6GQN · PDBe 6GQN · UniProt Q8DR57