Research workbench
Crystal structure of a flavin binding protein from thermotoga maritima, TM379
Analyse Crystal structure of a flavin binding protein from thermotoga maritima, TM379 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1MRZ
- Type
- protein
- Length
- 536 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Riboflavin KINASE/FMN adenylyltransferase
- UniProt
- Q9WZW1
- Pockets
- 11 · best druggability 0.87
Structure
x-ray diffraction · 2 distinct chains · 32% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Riboflavin KINASE/FMN adenylyltransferase | protein | 266 | 33% helix, 28% strand | Q9WZW1 |
| B | Riboflavin KINASE/FMN adenylyltransferase | protein | 270 | 32% helix, 28% strand | Q9WZW1 |
Ligands and binding sites
- CIT · Citric acid · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 722 | 0.87 | 0.91 | 58 | CIT |
| 2 | 372 | 0.67 | 0.80 | 37 | CIT |
| 3 | 85 | 0.58 | 0.87 | 20 | empty |
| 4 | 138 | 0.55 | 0.81 | 22 | empty |
| 5 | 189 | 0.48 | 0.76 | 36 | empty |
Interfaces
1 interface between chains.
- A–B · 1028 Ų buried · 15 hydrogen bonds · protein-protein
Compared structures
- 1MRZ · Crystal structure of a flavin binding protein from Thermotoga Maritima, TM379 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9WZW1
- Elsewhere: RCSB PDB 1MRZ · PDBe 1MRZ · UniProt Q9WZW1
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