Research workbench
Ctsr C-terminal domain with bound phospho-arginine
Analyse Ctsr C-terminal domain with bound phospho-arginine in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6FH4
- Type
- protein
- Length
- 304 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional regulator ctsr
- UniProt
- A0A0C3K8Q6
- Ligands
- RPI, PO4
- Pockets
- 1 · best druggability 0.52
Structure
x-ray diffraction · 3 distinct chains · 74% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Transcriptional regulator ctsr | protein | 75 | 75% helix, 0% strand | A0A0C3K8Q6 |
| C | Transcriptional regulator ctsr | protein | 78 | 73% helix, 0% strand | A0A0C3K8Q6 |
| D | Transcriptional regulator ctsr | protein | 76 | 74% helix, 0% strand | A0A0C3K8Q6 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 229 | 0.52 | 0.76 | 25 | empty |
Interfaces
3 interfaces between chains.
- C–D · 1018 Ų buried · 13 hydrogen bonds · protein-protein
- A–B · 969 Ų buried · 15 hydrogen bonds · protein-protein
- B–C · 456 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 6FH4 · CtsR C-terminal domain with bound phospho-arginine · the same entry in another collection · chain D against D, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0C3K8Q6
- Elsewhere: RCSB PDB 6FH4 · PDBe 6FH4 · UniProt A0A0C3K8Q6
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