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Crystal structure of C-terminal modified tau peptide-hybrid 4.2F-I with 14-3-3SIGMA
Analyse Crystal structure of C-terminal modified tau peptide-hybrid 4.2F-I with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6FAV
- Type
- protein
- Length
- 470 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P31947
- Ligands
- D3Q, ACE, NA, CL
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 229 | — | P31947 |
| B | — | protein | 7 | — | — |
| C | — | protein | 228 | — | P31947 |
| D | — | protein | 6 | — | — |
Ligands and binding sites
- D3Q · (2~{R})-2-[(~{R})-(3-methoxyphenyl)-phenyl-methyl]pyrrolidine · ligand · 2 copies · chains A, B, C, D
- ACE · Acetyl group · ligand · chains B
- NA · Sodium ion · metal · 5 copies · chains A, C
- CL · Chloride ion · ion · 2 copies · chains C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6FAV · Crystal structure of C-terminal modified Tau peptide-hybrid 4.2f-I with 14-3-3sigma · the same entry in another collection · chain A against A, TM-score 1.00
- P31947 · AlphaFold monomer V2.0 prediction for 14-3-3 protein sigma (P31947) · a predicted model of the same protein · chain C against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31947
- Elsewhere: RCSB PDB 6FAV · PDBe 6FAV · UniProt P31947
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