PDZK1 domain 4 in complex with C-terminal peptide of human PEPT2.

Structure

x-ray diffraction · 2 distinct chains · 15% helix, 38% strand (DSSP).

Ligands and binding sites

• GOL · Glycerol · additive · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 591 Ų buried · 14 hydrogen bonds · protein-protein

Compared structures

• 6EZI · PDZK1 domain 4 in complex with C-terminal peptide of human PepT2. · the same entry in another collection · chain A against A, TM-score 1.00
• Q5T2W1 · AlphaFold monomer V2.0 prediction for NA(+)/H(+) exchange regulatory cofactor nhe-RF3… · a predicted model of the same protein · chain A against A, TM-score 0.94
• Q16348 · AlphaFold monomer V2.0 prediction for solute carrier family 15 member 2 (Q16348) · a predicted model of the same protein · chain B against A, TM-score 0.79

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q5T2W1
• Every structure of UniProt Q16348
• Elsewhere: RCSB PDB 6EZI · PDBe 6EZI · UniProt Q5T2W1 · UniProt Q16348