UniProt Q5T2W1
Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (Q5T2W1)
Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (UniProt Q5T2W1): 12 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5T2W1
- Protein
- Na(+)/H(+) exchange regulatory cofactor NHE-RF3
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 7 · 0 records with a druggable one
Structures
13 records of Q5T2W1 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2EEI | Solution Structure of Second PDZ domain of PDZ Domain Containing Protein 1 | solution nmr | A | — | — |
| 2EEI | Solution structure of second PDZ domain of PDZ domain containing protein 1 | solution nmr | A | — | — |
| 2EEJ | Solution Structure of Fourth PDZ domain of PDZ Domain Containing Protein 1 | solution nmr | A | — | — |
| 2EEJ | Solution structure of fourth PDZ domain of PDZ domain containing protein 1 | solution nmr | A | — | — |
| 2VSP | Crystal structure of the fourth PDZ domain of PDZ domain-containing protein 1 | x-ray diffraction | A, B, C, D | — | — |
| 2VSP | Crystal structure of the fourth PDZ domain of PDZ domain-containing protein 1 | x-ray diffraction | A, B, C, D | — | — |
| 3TMH | Crystal structure of dual-specific A-kinase anchoring protein 2 in complex with cAMP-dependent… | x-ray diffraction | A, E, I | — | — |
| 3TMH | Crystal structure of dual-specific a-kinase anchoring protein 2 in complex with camp-dependent… | x-ray diffraction | A, E, I | — | — |
| 4Q2P | NHERF3 PDZ2 in Complex with a Phage-Derived Peptide | x-ray diffraction | A, B, C | — | — |
| 4Q2P | NHERF3 PDZ2 in complex with a phage-derived peptide | x-ray diffraction | A, B, C | — | — |
| 6EZI | PDZK1 domain 4 in complex with C-terminal peptide of human PepT2. | x-ray diffraction | A | — | — |
| 6EZI | PDZK1 domain 4 in complex with C-terminal peptide of human PEPT2. | x-ray diffraction | A | — | — |
| Q5T2W1 | AlphaFold monomer V2.0 prediction for NA(+)/H(+) exchange regulatory cofactor nhe-RF3 (Q5T2W1) | predicted | A | — | 7 (best 0.49) |
Experiment against prediction
- 2VSP chain B against the predicted model Q5T2W1: TM-score 0.97, RMSD 0.63 Å
- 2VSP chain B against the predicted model Q5T2W1: TM-score 0.97, RMSD 0.63 Å
- 2VSP chain A against the predicted model Q5T2W1: TM-score 0.96, RMSD 0.75 Å
- 2VSP chain A against the predicted model Q5T2W1: TM-score 0.96, RMSD 0.75 Å
- 3TMH chain A against the predicted model Q5T2W1: TM-score 0.96, RMSD 0.73 Å
- 3TMH chain A against the predicted model Q5T2W1: TM-score 0.96, RMSD 0.73 Å
- 6EZI chain A against the predicted model Q5T2W1: TM-score 0.94, RMSD 0.78 Å
- 6EZI chain A against the predicted model Q5T2W1: TM-score 0.94, RMSD 0.78 Å
- 4Q2P chain A against the predicted model Q5T2W1: TM-score 0.91, RMSD 1.72 Å
- 4Q2P chain A against the predicted model Q5T2W1: TM-score 0.91, RMSD 1.72 Å
Elsewhere
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