Research workbench
The GH43, beta 1,3 galactosidase, BT0265
Analyse The GH43, beta 1,3 galactosidase, BT0265 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6EUF
- Type
- protein
- Length
- 1,888 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta-glucanase
- UniProt
- Q8AB46
- Ligands
- GAL, AHR, BDP, RAM
- Pockets
- 20 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 6% helix, 45% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Beta-glucanase | protein | 472 | 6% helix, 45% strand | Q8AB46 |
Ligands and binding sites
- GAL · beta-D-galactopyranose · sugar · 8 copies · chains A, B, C, D
- AHR · alpha-L-arabinofuranose · sugar · 8 copies · chains A, B, C, D
- BDP · beta-D-glucopyranuronic acid · sugar · 4 copies · chains A, B, C, D
- RAM · alpha-L-rhamnopyranose · sugar · 2 copies · chains B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 15 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 748 | 0.81 | 0.85 | 114 | empty |
| 2 | 761 | 0.78 | 0.82 | 98 | empty |
| 3 | 128 | 0.64 | 0.87 | 26 | GAL |
| 4 | 169 | 0.62 | 0.84 | 32 | GAL |
| 5 | 138 | 0.61 | 0.85 | 32 | GAL |
Interfaces
4 interfaces between chains.
- A–B · 902 Ų buried · 14 hydrogen bonds · protein-protein
- C–D · 855 Ų buried · 12 hydrogen bonds · protein-protein
- B–C · 329 Ų buried · 4 hydrogen bonds · protein-protein
- A–D · 327 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 6EUF · The GH43, Beta 1,3 Galactosidase, BT0265 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8AB46
- Elsewhere: RCSB PDB 6EUF · PDBe 6EUF · UniProt Q8AB46
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.