Research workbench
Yoph PTP1B wpd loop chimera 2 ptpase bound to vanadate
Analyse Yoph PTP1B wpd loop chimera 2 ptpase bound to vanadate in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6DR7
- Type
- protein
- Length
- 282 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Targeted effector protein
- UniProt
- O68720
- Ligands
- VO4
- Pockets
- 3 · best druggability 0.45
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Targeted effector protein | protein | 282 | 40% helix, 21% strand | O68720 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 146 | 0.45 | 0.77 | 22 | empty |
| 2 | 102 | 0.40 | 0.77 | 19 | ACT, VO4 |
| 3 | 50 | 0.33 | 0.78 | 14 | empty |
Compared structures
- 6DR7 · YopH PTP1B WPD loop Chimera 2 PTPase bound to vanadate · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O68720
- Elsewhere: RCSB PDB 6DR7 · PDBe 6DR7 · UniProt O68720
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