Research workbench
Structure of lpne effector protein from legionella pneumophila (sp. philadelphia)
Analyse Structure of lpne effector protein from legionella pneumophila (sp.… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6DEH
- Type
- protein
- Length
- 650 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tpr repeat protein, protein-protein interaction
- UniProt
- Q5ZTE0
- Ligands
- NI
- Pockets
- 2 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 70% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Tpr repeat protein, protein-protein interaction | protein | 325 | 70% helix, 0% strand | Q5ZTE0 |
Ligands and binding sites
- NI · Nickel (II) ion · metal · 3 copies · chains A, B
- GOL · Glycerol · additive · 2 copies · chains A, B
- PEG · Di(hydroxyethyl)ether · additive · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 708 | 0.74 | 0.80 | 71 | PEG |
| 2 | 88 | 0.32 | 0.73 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 2987 Ų buried · 47 hydrogen bonds · protein-protein
Compared structures
- 6DEH · Structure of LpnE Effector Protein from Legionella pneumophila (sp. Philadelphia) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5ZTE0
- Elsewhere: RCSB PDB 6DEH · PDBe 6DEH · UniProt Q5ZTE0
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