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Residue assignment correction to the voltage gated calcium CAV1.1 rabbit alpha 1 subunit pdb entries 3JBR & 5GJV

Analyse Residue assignment correction to the voltage gated calcium CAV1.1 rabbit alpha… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6BYO
Type
protein
Length
1,129 residues
Chains
1
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Voltage-dependent L-type calcium channel subunit alpha-1S
UniProt
P07293
Pockets
19 · best druggability 0.81

Structure

electron microscopy · 1 distinct chain · 64% helix, 2% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AVoltage-dependent L-type calcium channel subunit alpha-1Sprotein112964% helix, 2% strandP07293

Pockets

19 pockets found on a 1 Å grid, 12 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16290.810.8563empty
210210.740.7780empty
32940.640.8122empty
45350.640.7556empty
52110.530.7624empty

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

  • 6BYO · Residue assignment correction to the voltage gated calcium Cav1.1 rabbit alpha 1 subunit… · the same entry in another collection · chain A against A, TM-score 1.00
  • P07293 · AlphaFold monomer V2.0 prediction for voltage-dependent L-type calcium channel subunit… · a predicted model of the same protein · chain A against A, TM-score 0.98

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