Research workbench

Caspase-3 mutant- T152D

Analyse Caspase-3 mutant- T152D in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6BG4
Type: protein
Length: 475 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P42574
Ligands: ACE, 0QE, NA, CL, AZI

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	—	protein	141	—	P42574
E	—	protein	92	—	P42574
F	—	protein	93	—	P42574
C, D	—	protein	4	—	—

Ligands and binding sites

ACE · Acetyl group · ligand · 2 copies · chains E, C, F, D
0QE · Chloromethane · ligand · 2 copies · chains A, E, C, B, F, D
NA · Sodium ion · metal · 13 copies · chains A, E, B, F
CL · Chloride ion · ion · 2 copies · chains A, B
AZI · Azide ion · ion · chains A, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6BG4 · Caspase-3 Mutant- T152D · the same entry in another collection · chain D against D, TM-score 1.00
P42574 · AlphaFold monomer V2.0 prediction for caspase-3 (P42574) · a predicted model of the same protein · chain B against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P42574
Elsewhere: RCSB PDB 6BG4 · PDBe 6BG4 · UniProt P42574

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