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Trastuzumab Fab V3 with 5-diphenyl meditope variant

Analyse Trastuzumab Fab V3 with 5-diphenyl meditope variant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6BAH
Type
protein
Length
566 residues
Chains
5
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P01834, Q6GMX6, Q51918, Q2UW42
Ligands
ACE

Structure

x-ray diffraction · 5 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein214—P01834
B—protein223—Q6GMX6
E—protein63—Q51918
C—protein54—Q2UW42
D—protein12——

Ligands and binding sites

  • ACE · Acetyl group · ligand · chains E, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6BAH · Trastuzumab Fab v3 with 5-diphenyl meditope variant · the same entry in another collection · chain A against A, TM-score 1.00
  • P01834 · AlphaFold monomer V2.0 prediction for immunoglobulin kappa constant (P01834) · a predicted model of the same protein · chain A against A, TM-score 0.50

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