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UniProt P01834

cetuximab Fab light chain (P01834)

cetuximab Fab light chain (UniProt P01834): 87 experimental structures on GenesisL1, 6 ligands bound, 89 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P01834
Protein
cetuximab Fab light chain
Experimental structures
87
Predicted models
0
Ligands
6
Pockets
89 · 15 records with a druggable one

Structures

87 records of P01834 in the MolNFT archive: 87 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
1A4JDiels alder catalytic antibody germline precursorx-ray diffractionL, A——
1A4JDiels alder catalytic antibody germline precursorx-ray diffractionL, A——
1A4KDiels alder catalytic antibody with transition state analoguex-ray diffractionL, A——
1A4KDiels alder catalytic antibody with transition state analoguex-ray diffractionL, A——
1D5BUnliganded mature oxy-cope catalytic antibodyx-ray diffractionA, L——
1D5BUnliganded mature oxy-cope catalytic antibodyx-ray diffractionA, L——
1D5IUnliganded germline precursor of an oxy-cope catalytic antibodyx-ray diffractionL——
1D5IUnliganded germline precursor of an oxy-cope catalytic antibodyx-ray diffractionL——
1D6VConformation effects in biological catalysis introduced by oxy-cope antibody maturationx-ray diffractionL——
1D6VConformation effects in biological catalysis introduced by oxy-cope antibody maturationx-ray diffractionL——
1HKLFree and liganded form of an esterolytic catalytic antibodyx-ray diffractionL——
1HKLFree and liganded form of an esterolytic catalytic antibodyx-ray diffractionL——
1I7ZAntibody GNC92H2 bound to ligandx-ray diffractionA, C——
1I7ZAntibody GNC92H2 bound to ligandx-ray diffractionA, C——
1MIMIgG Fab fragment (CD25-binding)x-ray diffractionL——
1MIMIgG Fab fragment (CD25-binding)x-ray diffractionL——
1UCBStructure of uncomplexed Fab compared to complex (1CLY, 1CLZ)x-ray diffractionL——
1UCBStructure of uncomplexed Fab compared to complex (1CLY, 1CLZ)x-ray diffractionL——
3O11Anti-beta-amyloid antibody c706 fab in space group c2x-ray diffractionL, A——
3O11Anti-beta-amyloid antibody C706 Fab in space group C2x-ray diffractionL, A——
3QCTCrystal structure of the humanized apo LT3015 anti-lysophosphatidic acid antibody Fab fragmentx-ray diffractionL——
3QCTCrystal structure of the humanized apo LT3015 anti-lysophosphatidic acid antibody Fab fragmentx-ray diffractionL——
3QCUCrystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (14:0)x-ray diffractionL, M——
3QCUCrystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (14:0)x-ray diffractionL, M——
3QCVCrystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (18:2)x-ray diffractionL, M——
3QCVCrystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (18:2)x-ray diffractionL, M——
3U0WAD related murine antibody Fragmentx-ray diffractionL——
3U0WAd related murine antibody fragmentx-ray diffractionL——
3U7WCrystal structure of NIH45-46 Fabx-ray diffractionL——
3U7WCrystal structure of NIH45-46 Fabx-ray diffractionL——
3U7YStructure of NIH45-46 Fab in complex with gp120 of 93TH057 HIVx-ray diffractionL——
3U7YStructure of NIH45-46 Fab in complex with GP120 of 93TH057 HIVx-ray diffractionL——
3VH8KIR3DL1 in complex with HLA-B*5701x-ray diffractionC, F——
3VH8KIR3DL1 in complex with HLA-B*5701x-ray diffractionC, F——
3X11Crystal structure of HLA-B*57:01.I80N.L82R.R83Gx-ray diffractionC——
3X11Crystal structure of HLA-B*57:01.I80N.L82R.R83Gx-ray diffractionC——
3X12Crystal structure of HLA-B*57:01.I80Nx-ray diffractionC——
3X12Crystal structure of HLA-B*57:01.I80Nx-ray diffractionC——
4D9RInhibiting Alternative Pathway Complement Activation by Targeting the Exosite on Factor Dx-ray diffractionL, D——
4D9RInhibiting alternative pathway complement activation by targeting the exosite on factor Dx-ray diffractionL, D——
4YDVStructure of the antibody 7B2 that captures HIV-1 virionsx-ray diffractionL, A——
4YDVStructure of the antibody 7B2 that captures HIV-1 virionsx-ray diffractionL, A——
5B38KIR3DL1*005 in complex with HLA-B*57:01x-ray diffractionC——
5B38KIR3DL1*005 in complex with HLA-B*57:01x-ray diffractionC——
5B39KIR3DL1*015 in complex with HLA-B*57:01x-ray diffractionC—1 (best 0.61)
5B39KIR3DL1*015 in complex with HLA-B*57:01x-ray diffractionC——
5C7KCrystal structure BG505 SOSIP gp140 HIV-1 Env trimer bound to broadly neutralizing antibodies…x-ray diffractionF——
5C7KCrystal structure BG505 sosip GP140 HIV-1 env trimer bound to broadly neutralizing antibodies…x-ray diffractionF——
5ESVCrystal Structure of Broadly Neutralizing Antibody CH03, Isolated from Donor CH0219, in Complex…x-ray diffractionB, D, LNAG, BMA, MAN—
5ESVCrystal structure of broadly neutralizing antibody CH03, isolated from donor CH0219, in complex…x-ray diffractionB, D, L——
5ESZCrystal Structure of Broadly Neutralizing Antibody CH04, Isolated from Donor CH0219, in Complex…x-ray diffractionL, BNAG, BMA, MAN—
5ESZCrystal structure of broadly neutralizing antibody CH04, isolated from donor CH0219, in complex…x-ray diffractionL, B——
5EWICrystal Structure of the Human Fab VRC38.01, an HIV-1 V1V2-Directed Neutralizing Antibody Isolated…x-ray diffractionL—4 (best 0.60)
5EWICrystal structure of the human Fab VRC38.01, an HIV-1 V1V2-directed neutralizing antibody isolated…x-ray diffractionL——
5VEBCrystal structure of a Fab binding to extracellular domain 5 of Cadherin-6x-ray diffractionB, L——
5VEBCrystal structure of a Fab binding to extracellular domain 5 of cadherin-6x-ray diffractionB, L——
5VIYBG505 SOSIP.664 in complex with broadly neutralizing antibodies BG1 and 8ANC195electron microscopyG, IMAN, BMA2 (best 0.75)
5VIYBG505 SOSIP.664 in complex with broadly neutralizing antibodies BG1 and 8ANC195electron microscopyG, IMAN—
6AU5Structure of cetuximab with aminoheptanoic acid-linked n-butylarginine meditope variantx-ray diffractionA, CSO48 (best 0.72)
6AU5Structure of cetuximab with aminoheptanoic acid-linked N-butylarginine meditope variantx-ray diffractionA, CSO4—

27 records more on the page itself.

Ligands

  • SO4 · Sulfate ion · in 8 records
  • MAN · alpha-D-mannopyranose · in 6 records
  • BMA · beta-D-mannopyranose · in 3 records
  • 011 · 7-aminoheptanoic acid · in 2 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
  • ACE · Acetyl group · in 1 record

Elsewhere

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