Research workbench

Solution structure of RAP1B/TALIN complex

Analyse Solution structure of RAP1B/TALIN complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6BA6
Type: protein
Length: 253 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Talin-1; RAS-related protein rap-1B
UniProt: P26039, P61224
Pockets: 2 · best druggability 0.40

Structure

solution nmr · 2 distinct chains · 27% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Talin-1	protein	86	17% helix, 21% strand	P26039
B	RAS-related protein rap-1B	protein	167	32% helix, 22% strand	P61224

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	64	0.40	0.80	16	empty
2	57	0.25	0.72	19	empty

Interfaces

1 interface between chains.

A–B · 873 Å² buried · 16 hydrogen bonds · protein-protein

Compared structures

6BA6 · Solution structure of Rap1b/talin complex · the same entry in another collection · chain A against A, TM-score 1.00
P61224 · AlphaFold monomer V2.0 prediction for RAS-related protein rap-1B (P61224) · a predicted model of the same protein · chain B against A, TM-score 0.92
P26039 · AlphaFold monomer V2.0 prediction for talin-1 (P26039) · a predicted model of the same protein · chain A against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P26039
Every structure of UniProt P61224
Elsewhere: RCSB PDB 6BA6 · PDBe 6BA6 · UniProt P26039 · UniProt P61224

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.