Research workbench
Solution NMR structure of bcor in complex with AF9 (bcor-AF9)
Analyse Solution NMR structure of bcor in complex with AF9 (bcor-AF9) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6B7G
- Type
- protein
- Length
- 103 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein af-9; BCL-6 corepressor
- UniProt
- P42568, Q6W2J9
- Pockets
- 2 · best druggability 0.75
Structure
solution nmr · 2 distinct chains · 36% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein af-9 | protein | 70 | 53% helix, 11% strand | P42568 |
| B | BCL-6 corepressor | protein | 33 | 0% helix, 15% strand | Q6W2J9 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 113 | 0.75 | 0.95 | 27 | empty |
| 2 | 64 | 0.34 | 0.76 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 902 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 6B7G · Solution NMR structure of BCoR in complex with AF9 (BCoR-AF9) · the same entry in another collection · chain A against A, TM-score 1.00
- P42568 · AlphaFold monomer V2.0 prediction for protein af-9 (P42568) · a predicted model of the same protein · chain A against A, TM-score 0.83
- Q6W2J9 · AlphaFold monomer V2.0 prediction for BCL-6 corepressor (Q6W2J9) · a predicted model of the same protein · chain B against A, TM-score 0.29
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P42568
- Every structure of UniProt Q6W2J9
- Elsewhere: RCSB PDB 6B7G · PDBe 6B7G · UniProt P42568 · UniProt Q6W2J9
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