Research workbench

E52Q mutant form of uracil DNA glycosylase X from mycobacterium smegmatis.

Analyse E52Q mutant form of uracil DNA glycosylase X from mycobacterium smegmatis. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6AJQ
Type: protein
Length: 208 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uracil DNA glycosylase superfamily protein
UniProt: A0QP43
Ligands: SF4
Pockets: 1 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uracil DNA glycosylase superfamily protein	protein	208	42% helix, 12% strand	A0QP43

Ligands and binding sites

SF4 · Iron/sulfur cluster · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	125	0.55	0.83	27	empty

Compared structures

6AJQ · E52Q mutant form of Uracil DNA glycosylase X from Mycobacterium smegmatis. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0QP43
Elsewhere: RCSB PDB 6AJQ · PDBe 6AJQ · UniProt A0QP43

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