UniProt A0QP43
Type-4 uracil-DNA glycosylase (A0QP43)
Type-4 uracil-DNA glycosylase (UniProt A0QP43), EC 3.2.2.27: 22 experimental structures on GenesisL1, 5 ligands bound, 13 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0QP43
- Protein
- Type-4 uracil-DNA glycosylase
- EC
- 3.2.2.27
- Experimental structures
- 22
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 13 · 5 records with a druggable one
Structures
22 records of A0QP43 in the MolNFT archive: 22 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6AIL | CRYSTAL STRUCTURE AT 1.3 ANGSTROMS RESOLUTION OF A NOVEL UDG, UdgX, FROM Mycobacterium smegmatis | x-ray diffraction | A | SF4 | 1 (best 0.62) |
| 6AIL | Crystal structure at 1.3 ångströms resolution of a novel udg, udgx, from mycobacterium smegmatis | x-ray diffraction | A | SF4 | — |
| 6AJO | Complex form of uracil DNA glycosylase X and uracil-DNA. | x-ray diffraction | A | ORP, SF4, PO4, URA | — |
| 6AJP | Complex form of uracil DNA glycosylase X and deoxyuridine monophosphate. | x-ray diffraction | A | DU, SF4 | — |
| 6AJQ | E52Q mutant form of Uracil DNA glycosylase X from Mycobacterium smegmatis. | x-ray diffraction | A | SF4 | 1 (best 0.55) |
| 6AJQ | E52Q mutant form of uracil DNA glycosylase X from mycobacterium smegmatis. | x-ray diffraction | A | SF4 | — |
| 6AJR | Complex form of Uracil DNA glycosylase X and uracil | x-ray diffraction | A | SF4, URA | 1 (best 0.55) |
| 6AJR | Complex form of uracil DNA glycosylase X and uracil | x-ray diffraction | A | SF4, URA | — |
| 6AJS | H109S mutant form of Uracil DNA glycosylase X. | x-ray diffraction | A | SF4 | — |
| 6AJS | H109S mutant form of uracil DNA glycosylase X. | x-ray diffraction | A | SF4 | — |
| 6L5A | The structure of the udgx mutant H109E at a pre-excision state | x-ray diffraction | A | SF4 | — |
| 6L5B | The structure of the udgx mutant H109E at a post-excision state | x-ray diffraction | A | SF4 | — |
| 8IIG | Complex form of MsmUdgX H109A mutant and uracil- obtained from uracil DNA (ttUtt) post its cleavage… | x-ray diffraction | A | SF4, URA | 1 (best 0.48) |
| 8III | Complex form of MsmUdgX H109C mutant and uracil- obtained from uracil DNA (ttUtt) post its cleavage… | x-ray diffraction | A | SF4, URA | 1 (best 0.49) |
| 8IIJ | H109G mutant of uracil DNA glycosylase X | x-ray diffraction | A | SF4 | 1 (best 0.54) |
| 8IIL | Complex form of MsmUdgX H109G mutant and uracil- obtained from uracil DNA (ttUtt) post its cleavage… | x-ray diffraction | A | SF4, URA | 1 (best 0.49) |
| 8IIM | H109K mutant of uracil DNA glycosylase X | x-ray diffraction | A | SF4 | 1 (best 0.45) |
| 8IIO | H109Q mutant of uracil DNA glycosylase X | x-ray diffraction | A | SF4 | 1 (best 0.44) |
| 8IIP | Complex form of MsmUdgX H109Q mutant and uracil- obtained from uracil DNA (ttUtt) post its cleavage… | x-ray diffraction | A | SF4, URA | 1 (best 0.43) |
| 8IIQ | MsmUdgX H109S/E52N double mutant | x-ray diffraction | A | SF4 | 1 (best 0.46) |
| 8IIR | MsmUdgX H109S/Q53A double mutant | x-ray diffraction | A | SF4 | 1 (best 0.55) |
| 8IIT | Complex form of MsmUdgX H109S/R184A double mutant and uracil- obtained from uracil DNA (ttUtt) post… | x-ray diffraction | A | SF4, URA | 1 (best 0.48) |
Ligands
Elsewhere
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