Research workbench
Structure of mouse TREX2
Analyse Structure of mouse TREX2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6A45
- Type
- protein
- Length
- 431 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Three prime repair exonuclease 2
- EC
- 3.1.11.2
- UniProt
- Q9R1A9
- Ligands
- PO4
- Pockets
- 3 · best druggability 0.63
Structure
x-ray diffraction · 2 distinct chains · 43% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Three prime repair exonuclease 2 (EC 3.1.11.2) | protein | 220 | 42% helix, 18% strand | Q9R1A9 |
| B | Three prime repair exonuclease 2 (EC 3.1.11.2) | protein | 211 | 43% helix, 20% strand | Q9R1A9 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 407 | 0.63 | 0.78 | 35 | empty |
| 2 | 245 | 0.52 | 0.76 | 32 | empty |
| 3 | 189 | 0.47 | 0.75 | 35 | empty |
Interfaces
1 interface between chains.
- A–B · 1550 Ų buried · 39 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9R1A9
- Elsewhere: RCSB PDB 6A45 · PDBe 6A45 · UniProt Q9R1A9
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.