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Binding and enhanced binding between key immunity proteins TRAF6 and tifa

Analyse Binding and enhanced binding between key immunity proteins TRAF6 and tifa in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5ZUJ
Type
protein
Length
165 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
TNF receptor-associated factor 6; Peptide 170-184 from traf-interacting protein with fha…
EC
2.3.2.27
UniProt
Q9Y4K3, Q96CG3

Structure

x-ray diffraction · 2 distinct chains · 15% helix, 42% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATNF receptor-associated factor 6 (EC 2.3.2.27)protein15316% helix, 42% strandQ9Y4K3
IPeptide 170-184 from traf-interacting protein with fha domain-containing protein aprotein120% helix, 33% strandQ96CG3

Interfaces

1 interface between chains.

  • A–I · 617 Ų buried · 19 hydrogen bonds · protein-protein

Compared structures

  • 5ZUJ · Binding and Enhanced Binding between Key Immunity Proteins TRAF6 and TIFA · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9Y4K3 · AlphaFold monomer V2.0 prediction for TNF receptor-associated factor 6 (Q9Y4K3) · a predicted model of the same protein · chain A against A, TM-score 0.98
  • Q96CG3 · AlphaFold monomer V2.0 prediction for traf-interacting protein with fha domain-containing… · a predicted model of the same protein · chain I against A, TM-score 0.45

Analyse

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