UniProt Q9Y4K3
TNF receptor-associated factor 6 (Q9Y4K3)
TNF receptor-associated factor 6 (UniProt Q9Y4K3), EC 2.3.2.27: 25 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q9Y4K3
- Protein
- TNF receptor-associated factor 6
- EC
- 2.3.2.27
- Experimental structures
- 25
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
26 records of Q9Y4K3 in the MolNFT archive: 25 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1LB4 | TRAF6 apo structure | x-ray diffraction | A | — | — |
| 1LB4 | TRAF6 apo structure | x-ray diffraction | A | — | — |
| 1LB5 | TRAF6-RANK Complex | x-ray diffraction | A | — | — |
| 1LB5 | TRAF6-rank complex | x-ray diffraction | A | — | — |
| 1LB6 | TRAF6-CD40 Complex | x-ray diffraction | A | — | — |
| 1LB6 | TRAF6-CD40 complex | x-ray diffraction | A | — | — |
| 2ECI | Solution structure of the RING domain of the human TNF receptor-associated factor 6 protein | solution nmr | A | ZN | — |
| 2ECI | Solution structure of the ring domain of the human TNF receptor- associated factor 6 protein | solution nmr | A | — | — |
| 2JMD | Solution Structure of the Ring Domain of Human TRAF6 | solution nmr | A | — | — |
| 2JMD | Solution structure of the ring domain of human TRAF6 | solution nmr | A | — | — |
| 3HCS | Crystal structure of the N-terminal domain of TRAF6 | x-ray diffraction | A, B | — | — |
| 3HCS | Crystal structure of the N-terminal domain of TRAF6 | x-ray diffraction | A, B | — | — |
| 3HCT | Crystal structure of TRAF6 in complex with Ubc13 in the P1 space group | x-ray diffraction | A | — | — |
| 3HCT | Crystal structure of TRAF6 in complex with UBC13 in the P1 space group | x-ray diffraction | A | — | — |
| 3HCU | Crystal structure of TRAF6 in complex with Ubc13 in the C2 space group | x-ray diffraction | A, C | — | — |
| 3HCU | Crystal structure of TRAF6 in complex with UBC13 in the C2 space group | x-ray diffraction | A, C | — | — |
| 4Z8M | Crystal structure of the MAVS-TRAF6 complex | x-ray diffraction | A, B | — | — |
| 4Z8M | Crystal structure of the mavs-TRAF6 complex | x-ray diffraction | A, B | — | — |
| 5ZUJ | Binding and Enhanced Binding between Key Immunity Proteins TRAF6 and TIFA | x-ray diffraction | A | — | — |
| 5ZUJ | Binding and enhanced binding between key immunity proteins TRAF6 and tifa | x-ray diffraction | A | — | — |
| 6A33 | Binding and Enhanced Binding between Key Immunity Proteins TRAF6 and TIFA | x-ray diffraction | A | — | — |
| 6A33 | Binding and enhanced binding between key immunity proteins TRAF6 and tifa | x-ray diffraction | A | — | — |
| 7L3L | Structure of TRAF5 and TRAF6 RING Hetero dimer | x-ray diffraction | B, D | ZN | 1 (best 0.46) |
| 7L3L | Structure of TRAF5 and TRAF6 ring hetero dimer | x-ray diffraction | B, D | ZN | — |
| 8HZ2 | Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) N-terminal Domain | x-ray diffraction | A, B | ZN | — |
| Q9Y4K3 | AlphaFold monomer V2.0 prediction for TNF receptor-associated factor 6 (Q9Y4K3) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 4 records
Experiment against prediction
- 4Z8M chain A against the predicted model Q9Y4K3: TM-score 0.98, RMSD 0.72 Å
- 4Z8M chain A against the predicted model Q9Y4K3: TM-score 0.98, RMSD 0.72 Å
- 3HCS chain A against the predicted model Q9Y4K3: TM-score 0.98, RMSD 0.63 Å
- 3HCS chain A against the predicted model Q9Y4K3: TM-score 0.98, RMSD 0.63 Å
- 6A33 chain A against the predicted model Q9Y4K3: TM-score 0.98, RMSD 0.76 Å
- 6A33 chain A against the predicted model Q9Y4K3: TM-score 0.98, RMSD 0.76 Å
- 7L3L chain D against the predicted model Q9Y4K3: TM-score 0.98, RMSD 0.55 Å
- 7L3L chain D against the predicted model Q9Y4K3: TM-score 0.98, RMSD 0.55 Å
- 5ZUJ chain A against the predicted model Q9Y4K3: TM-score 0.98, RMSD 0.87 Å
- 5ZUJ chain A against the predicted model Q9Y4K3: TM-score 0.98, RMSD 0.87 Å
Elsewhere
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