Research workbench
Domain swapped dimer crystal structure of LOOP1 deletion mutant in single-chain monellin
Analyse Domain swapped dimer crystal structure of LOOP1 deletion mutant in single-chain… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5XFU
- Type
- protein
- Length
- 449 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Monellin chain B,MONELLIN chain a
- UniProt
- P02882, P02881
- Pockets
- 1 · best druggability 0.46
Structure
x-ray diffraction · 2 distinct chains · 19% helix, 54% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C, D, E | Monellin chain B,MONELLIN chain a | protein | 90 | 19% helix, 53% strand | P02882, P02881 |
| B | Monellin chain B,MONELLIN chain a | protein | 89 | 19% helix, 54% strand | P02882, P02881 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 187 | 0.46 | 0.75 | 28 | empty |
Interfaces
9 interfaces between chains.
- A–B · 2716 Ų buried · 36 hydrogen bonds · protein-protein
- C–D · 2596 Ų buried · 32 hydrogen bonds · protein-protein
- B–D · 305 Ų buried · 5 hydrogen bonds · protein-protein
- D–E · 276 Ų buried · 0 hydrogen bonds · protein-protein
- B–C · 148 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 5XFU · Domain swapped dimer crystal structure of loop1 deletion mutant in Single-chain Monellin · the same entry in another collection · chain E against E, TM-score 1.00
- P02882 · AlphaFold monomer V2.0 prediction for monellin chain B (P02882) · a predicted model of the same protein · chain B against A, TM-score 0.53
- P02881 · AlphaFold monomer V2.0 prediction for monellin chain a (P02881) · a predicted model of the same protein · chain B against A, TM-score 0.48
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02882
- Every structure of UniProt P02881
- Elsewhere: RCSB PDB 5XFU · PDBe 5XFU · UniProt P02882 · UniProt P02881
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