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Crystal structure of the medaka fish taste receptor T1R2A-T1R3 ligand binding domains in complex with L-glutamate

Analyse Crystal structure of the medaka fish taste receptor T1R2A-T1R3 ligand binding… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5X2P
Type
protein
Length
2,598 residues
Chains
8
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
A0A173M0G2, A0A173M094
Ligands
NAG, BMA, NA, CA, CL

Structure

x-ray diffraction · 8 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein428—A0A173M0G2
B—protein454—A0A173M094
C—protein431—A0A173M0G2
D—protein415—A0A173M094
H—protein219——
L—protein217——
J—protein218——
K—protein216——

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 27 copies · chains A, B, C, D
  • BMA · beta-D-mannopyranose · sugar
  • NA · Sodium ion · metal · 2 copies · chains A, C
  • CA · Calcium ion · metal · chains K
  • CL · Chloride ion · ion · 2 copies · chains B, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 5X2P · Crystal structure of the medaka fish taste receptor T1r2a-T1r3 ligand binding domains in… · the same entry in another collection · chain L against L, TM-score 1.00

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