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Hepatitis B virus core protein Y132A mutant in P 41 21 2 space group

Analyse Hepatitis B virus core protein Y132A mutant in P 41 21 2 space group in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5WTW
Type: protein
Length: 284 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Core protein
UniProt: L7R9I1
Ligands: CL
Pockets: 2 · best druggability 0.59

Structure

x-ray diffraction · 1 distinct chain · 70% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Core protein	protein	142	70% helix, 0% strand	L7R9I1

Ligands and binding sites

CL · Chloride ion · ion · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	109	0.59	0.85	22	empty
2	64	0.47	0.84	17	empty

Interfaces

1 interface between chains.

A–B · 2119 Å² buried · 20 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

5WTW · Hepatitis B virus core protein Y132A mutant in P 41 21 2 Space Group · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt L7R9I1
Elsewhere: RCSB PDB 5WTW · PDBe 5WTW · UniProt L7R9I1

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