UniProt L7R9I1
Capsid protein (L7R9I1)
Capsid protein (UniProt L7R9I1): 13 experimental structures on GenesisL1, 8 ligands bound, 81 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- L7R9I1
- Protein
- Capsid protein
- Experimental structures
- 13
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 81 · 7 records with a druggable one
Structures
13 records of L7R9I1 in the MolNFT archive: 13 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GMZ | Hepatitis B virus core protein Y132A mutant in complex with 4-methyl heteroaryldihydropyrimidine | x-ray diffraction | A, B, C, D, E, F | 6XU, CL | 10 (best 0.72) |
| 5GMZ | Hepatitis B virus core protein Y132A mutant in complex with 4-methyl heteroaryldihydropyrimidine | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5T2P | Hepatitis B virus core protein Y132A mutant in complex with sulfamoylbenzamide (SBA_R01) | x-ray diffraction | A, B, C, D, E, F | K89, CL | — |
| 5WRE | Hepatitis B virus core protein Y132A mutant in complex with heteroaryldihydropyrimidine (HAP_R01) | x-ray diffraction | A, B, C, D, E, F | 7TL, CL | 11 (best 0.72) |
| 5WRE | Hepatitis B virus core protein Y132A mutant in complex with heteroaryldihydropyrimidine (HAP_R01) | x-ray diffraction | A, B, C, D, E, F | 7TL, CL | — |
| 5WTW | Hepatitis B virus core protein Y132A mutant in P 41 21 2 Space Group | x-ray diffraction | A, B | CL | 2 (best 0.59) |
| 5WTW | Hepatitis B virus core protein Y132A mutant in P 41 21 2 space group | x-ray diffraction | A, B | CL | — |
| 7S76 | HBV CAPSID Y132A WITH COMPOUND 10b AT 2.5A RESOLUTION | x-ray diffraction | A, B, C, D, E, F | 8EI | — |
| 7S76 | HBV capsid Y132A with compound 10B at 2.5A resolution | x-ray diffraction | A, B, C, D, E, F | 8EI | — |
| 8GBU | Hepatitis B capsid Y132A mutant with compound AB-506 | x-ray diffraction | A, B, C, D, E, F | YWE | 14 (best 0.70) |
| 8GHS | Empty HBV Cp183 capsid with importin-beta, subparticle reconstruction at 2-fold location | electron microscopy | B, A, D, C, F, E, H, G, J, I, L, K | — | 20 (best 0.79) |
| 8GIH | Structure of Hepatitis B Virus Capsid Y132A mutant in complex with Compound 24 | x-ray diffraction | A, B, C, D, E, F | CL, ZMH | 10 (best 0.71) |
| 9C9V | HBV capsid with compound 3i | x-ray diffraction | A, B, C, D, E, F | A1AVK | 14 (best 0.65) |
Ligands
- CL · Chloride ion · in 7 records
- 7TL · (2S)-1-[[(4R)-4-(2-chloranyl-4-fluoranyl-phenyl)-5-methoxycarbonyl-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-4,4-bis(fluoranyl) pyrrolidine-2-carboxylic acid · in 2 records
- 8EI · (1-methyl-1H-1,2,4-triazol-3-yl)methyl {(4S)-1-[(3-chloro-4-fluorophenyl)carbamoyl]-2-methyl-2,4,5,6-tetrahydrocyclopenta[c]pyrrol-4-yl}carbamate · in 2 records
- 6XU · (2S)-4,4-difluoro-1-[[(4S)-4-(4-fluorophenyl)-5-methoxycarbonyl-4-methyl-2-(1,3-thiazol-2-yl)-1H-pyrimidin-6-yl]methyl]pyrrolidine-2-carboxylic acid · in 1 record
- A1AVK · N'-(3-chloro-4-fluorophenyl)-N-(2-methylpropyl)-N-[(1R)-1-(1-oxo-1,2-dihydroisoquinolin-4-yl)ethyl]urea · in 1 record
- K89 · 4-fluoranyl-3-(4-oxidanylpiperidin-1-yl)sulfonyl-~{N}-[3,4,5-tris(fluoranyl)phenyl]benzamide · in 1 record
- YWE · (1-methyl-1H-1,2,4-triazol-3-yl)methyl {(1S)-4-[(3-chloro-4-fluorophenyl)carbamoyl]-7-fluoro-2,3-dihydro-1H-inden-1-yl}carbamate · in 1 record
- ZMH · (6S,8R)-N-(3-bromo-4-fluorophenyl)-8-fluoro-10-methyl-11-oxo-1,3,4,7,8,9,10,11-octahydro-2H-pyrido[4',3':3,4]pyrazolo[1,5-a][1,4]diazepine-2-carboxamide · in 1 record
Elsewhere
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