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Cryoem structure of the segment, dliikgisvhi, assembled into a triple- helical fibril

Analyse Cryoem structure of the segment, dliikgisvhi, assembled into a triple- helical… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5W7V
Type
protein
Length
88 residues
Chains
9
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Tar DNA-binding protein 43
UniProt
Q13148

Structure

electron microscopy · 3 distinct chains · 0% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
1, 3, 2, 6, 5, 4, 7Tar DNA-binding protein 43protein110% helix, 0% strandQ13148
0Tar DNA-binding protein 43protein60% helix, 0% strandQ13148
8Tar DNA-binding protein 43protein50% helix, 0% strandQ13148

Interfaces

12 interfaces between chains.

  • 3–2 · 179 Ų buried · 2 hydrogen bonds · protein-protein
  • 5–4 · 162 Ų buried · 2 hydrogen bonds · protein-protein
  • 1–0 · 136 Ų buried · 0 hydrogen bonds · protein-protein
  • 1–2 · 122 Ų buried · 1 hydrogen bond · protein-protein
  • 6–5 · 120 Ų buried · 0 hydrogen bonds · protein-protein

Compared structures

  • 5W7V · CryoEM structure of the segment, DLIIKGISVHI, assembled into a triple-helical fibril · the same entry in another collection · chain 8 against 8, TM-score 1.00
  • Q13148 · AlphaFold monomer V2.0 prediction for tar DNA-binding protein 43 (Q13148) · a predicted model of the same protein · chain 8 against A, TM-score 0.88

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