Influenza virus neuraminidase N9 in complex with 4-deoxygenated 2,3- difluoro-N-acetylneuraminic acid

Structure

x-ray diffraction · 1 distinct chain.

Ligands and binding sites

• 9SG · (2R,3R,5R,6R)-5-acetamido-2,3-bis(fluoranyl)-6-[(1R, 2R)-1,2,3-tris(oxidanyl)propyl]oxane-2-carboxylic acid · ligand · chains A
• 9WM · (2~{R},3~{R},5~{R})-3-acetamido-5-fluoranyl-2-[(1~{R}, 2~{R})-1,2,3-tris(oxidanyl)propyl]-2,3,4,5-tetrahydropyran-1-ium-6-carboxylic acid · ligand · chains A
• 9VP · 5-acetamido-2,6-anhydro-3,4,5-trideoxy-3-fluoro-D-erythro-L-gluco-nononic acid · ligand · chains A
• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 5 copies · chains A
• MAN · alpha-D-mannopyranose · sugar · 5 copies
• BMA · beta-D-mannopyranose · sugar
• CA · Calcium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 5W26 · Influenza virus neuraminidase N9 in complex with 4-deoxygenated… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P03472
• Elsewhere: RCSB PDB 5W26 · PDBe 5W26 · UniProt P03472