Research workbench
Structure of S. cerevisiae ULP2-TOF2-CSM1 complex
Analyse Structure of S. cerevisiae ULP2-TOF2-CSM1 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5V3N
- Type
- protein
- Length
- 142 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Monopolin complex subunit CSM1; ULP2P,TOPOISOMERASE 1-associated factor 2 chimera
- UniProt
- P25651, H0GHZ9, Q02208
- Pockets
- 1 · best druggability 0.41
Structure
x-ray diffraction · 2 distinct chains · 37% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Monopolin complex subunit CSM1 | protein | 109 | 40% helix, 37% strand | P25651 |
| B | ULP2P,TOPOISOMERASE 1-associated factor 2 chimera | protein | 33 | 27% helix, 6% strand | H0GHZ9, Q02208 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 100 | 0.41 | 0.76 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1449 Ų buried · 27 hydrogen bonds · protein-protein
Compared structures
- 5V3N · Structure of S. cerevisiae Ulp2-Tof2-Csm1 complex · the same entry in another collection · chain A against A, TM-score 1.00
- P25651 · AlphaFold monomer V2.0 prediction for monopolin complex subunit CSM1 (P25651) · a predicted model of the same protein · chain A against A, TM-score 0.96
- Q02208 · AlphaFold monomer V2.0 prediction for topoisomerase 1-associated factor 2 (Q02208) · a predicted model of the same protein · chain B against A, TM-score 0.27
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P25651
- Every structure of UniProt H0GHZ9
- Every structure of UniProt Q02208
- Elsewhere: RCSB PDB 5V3N · PDBe 5V3N · UniProt P25651 · UniProt H0GHZ9 · UniProt Q02208
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