UniProt Q02208
Topoisomerase 1-associated factor 2 (Q02208)
Topoisomerase 1-associated factor 2 (UniProt Q02208): 4 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q02208
- Protein
- Topoisomerase 1-associated factor 2
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 7 · 0 records with a druggable one
Structures
5 records of Q02208 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5HOI | Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Tof2. | x-ray diffraction | D, E, F | — | 3 (best 0.40) |
| 5HOI | Crystal structure of the carboxy-terminal domain of yeast CTF4 bound to TOF2. | x-ray diffraction | D, E, F | — | 3 (best 0.40) |
| 5V3N | Structure of S. cerevisiae Ulp2-Tof2-Csm1 complex | x-ray diffraction | B | — | — |
| 5V3N | Structure of S. cerevisiae ULP2-TOF2-CSM1 complex | x-ray diffraction | B | — | — |
| Q02208 | AlphaFold monomer V2.0 prediction for topoisomerase 1-associated factor 2 (Q02208) | predicted | A | — | 1 (best 0.43) |
Experiment against prediction
- 5HOI chain F against the predicted model Q02208: TM-score 0.88, RMSD 0.19 Å
- 5HOI chain F against the predicted model Q02208: TM-score 0.88, RMSD 0.19 Å
- 5HOI chain D against the predicted model Q02208: TM-score 0.74, RMSD 0.38 Å
- 5HOI chain D against the predicted model Q02208: TM-score 0.74, RMSD 0.38 Å
- 5V3N chain B against the predicted model Q02208: TM-score 0.27, RMSD 2.48 Å
- 5V3N chain B against the predicted model Q02208: TM-score 0.27, RMSD 2.48 Å
Elsewhere
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