Research workbench
Crystal structure of macrolide 2'-phosphotransferase mphb from escherichia COLI
Analyse Crystal structure of macrolide 2'-phosphotransferase mphb from escherichia COLI in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5UXA
- Type
- protein
- Length
- 301 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Macrolide 2'-phosphotransferase II
- UniProt
- O32553
- Ligands
- CA
- Pockets
- 4 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Macrolide 2'-phosphotransferase II | protein | 301 | 50% helix, 15% strand | O32553 |
Ligands and binding sites
- CA · Calcium ion · metal · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 297 | 0.59 | 0.78 | 30 | empty |
| 2 | 269 | 0.58 | 0.78 | 28 | empty |
| 3 | 67 | 0.40 | 0.80 | 14 | empty |
| 4 | 55 | 0.30 | 0.75 | 17 | empty |
Compared structures
- 5UXA · Crystal structure of macrolide 2'-phosphotransferase MphB from Escherichia coli · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O32553
- Elsewhere: RCSB PDB 5UXA · PDBe 5UXA · UniProt O32553
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