Research workbench
Crystal structure of the zn-bound human heavy-chain variant 122H-delta C-star with para-benzenedihydroxamate
Analyse Crystal structure of the zn-bound human heavy-chain variant 122H-delta C-star… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5UP8
- Type
- protein
- Length
- 176 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ferritin heavy chain
- EC
- 1.16.3.1
- UniProt
- P02794
- Ligands
- BYD, ZN, NA
- Pockets
- 2 · best druggability 0.37
Structure
x-ray diffraction · 1 distinct chain · 72% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ferritin heavy chain (EC 1.16.3.1) | protein | 176 | 72% helix, 0% strand | P02794 |
Ligands and binding sites
- BYD · N,N'-dihydroxybenzene-1,4-dicarboxamide · ligand · chains A
- ZN · Zinc ion · metal · 3 copies · chains A
- NA · Sodium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 59 | 0.37 | 0.80 | 14 | ZN |
| 2 | 61 | 0.32 | 0.75 | 15 | empty |
Compared structures
- 5UP8 · Crystal Structure of the Zn-bound Human Heavy-Chain variant 122H-delta C-star with… · the same entry in another collection · chain A against A, TM-score 1.00
- P02794 · AlphaFold monomer V2.0 prediction for ferritin heavy chain (P02794) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02794
- Elsewhere: RCSB PDB 5UP8 · PDBe 5UP8 · UniProt P02794
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