Research workbench
Apo-structure of mature growth differentiation factor 11
Analyse Apo-structure of mature growth differentiation factor 11 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5UHM
- Type
- protein
- Length
- 174 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- GROWTH/DIFFERENTIATION factor 11
- UniProt
- O95390
- Pockets
- 1 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 0% helix, 59% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | GROWTH/DIFFERENTIATION factor 11 | protein | 87 | 0% helix, 59% strand | O95390 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 157 | 0.69 | 0.88 | 27 | empty |
Interfaces
1 interface between chains.
- A–B · 966 Ų buried · 24 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 disulfide (disulfide).
Compared structures
- 5UHM · Apo-Structure of Mature Growth Differentiation Factor 11 · the same entry in another collection · chain A against A, TM-score 1.00
- O95390 · AlphaFold monomer V2.0 prediction for GROWTH/DIFFERENTIATION factor 11 (O95390) · a predicted model of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O95390
- Elsewhere: RCSB PDB 5UHM · PDBe 5UHM · UniProt O95390
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