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Pseudogtpase domain (PG1) of P190RHOGAP-B

Analyse Pseudogtpase domain (PG1) of P190RHOGAP-B in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5U4V
Type: protein
Length: 136 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Rho GTPase-activating protein 5
UniProt: Q13017
Pockets: 3 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Rho GTPase-activating protein 5	protein	136	46% helix, 29% strand	Q13017

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	79	0.55	0.86	16	empty
2	70	0.35	0.76	15	empty
3	72	0.31	0.74	19	empty

Compared structures

5U4V · pseudoGTPase domain (pG1) of p190RhoGAP-B · the same entry in another collection · chain A against A, TM-score 1.00
Q13017 · AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 5 (Q13017) · a predicted model of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q13017
Elsewhere: RCSB PDB 5U4V · PDBe 5U4V · UniProt Q13017

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