MolNFT v1 · #342536 · protein

AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 5 (Q13017)

Q13017: “AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 5 (Q13017)”. 16 pockets (best druggability 0.71). MolNFT v1 #342536 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q13017
Type: protein
Length: 1,502 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7c75F0f7d6d136A2b8D4C6C6e9b3D8a697949DF1
Molecule: Rho GTPase-activating protein 5
UniProt: Q13017
Pockets: 16 · best druggability 0.71

Structure

1 distinct chain · 41% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Rho GTPase-activating protein 5	protein	1502	41% helix, 10% strand	Q13017

Pockets

16 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	576	0.71	0.79	40	empty
2	367	0.69	0.82	52	empty
3	206	0.56	0.79	35	empty
4	148	0.49	0.78	16	empty
5	113	0.41	0.76	21	empty

Compared structures

5U4V · pseudoGTPase domain (pG1) of p190RhoGAP-B · an experimental structure of the same protein · chain A against A, TM-score 0.09
5U4V · Pseudogtpase domain (PG1) of P190RHOGAP-B · an experimental structure of the same protein · chain A against A, TM-score 0.09

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q13017
Elsewhere: UniProt Q13017 · AlphaFold DB Q13017

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