Research workbench
Structures of the lectin IV of griffonia simplicifolia and its complex with the lewis B human blood group determinant at 2.0 ångströms resolution
Analyse Structures of the lectin IV of griffonia simplicifolia and its complex with the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1LEC
- Type
- protein
- Length
- 243 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- West-central african legume lectin IV
- UniProt
- P24146
- Ligands
- NAG, FUC, MN, CA, SO4
Structure
x-ray diffraction · 1 distinct chain · 7% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | West-central african legume lectin IV | protein | 243 | 7% helix, 47% strand | P24146 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
- FUC · alpha-L-fucopyranose · sugar · chains A
- MN · Manganese (II) ion · metal · chains A
- CA · Calcium ion · metal · chains A
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Modifications
Observed in the structure: 1 glycan, 1 modified (N-glycosylation, cyclization).
Compared structures
- 1LEC · Structures of the lectin IV of griffonia simplicifolia and its complex with the lewis B… · the same entry in another collection · chain A against A, TM-score 1.00
- P24146 · AlphaFold monomer V2.0 prediction for lectin-4 (P24146) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P24146
- Elsewhere: RCSB PDB 1LEC · PDBe 1LEC · UniProt P24146
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