Research workbench
Glycosylasparaginase
Analyse Glycosylasparaginase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1AYY
- Type
- protein
- Length
- 565 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glycosylasparaginase
- EC
- 3.5.1.26
- UniProt
- Q47898
- Pockets
- 5 · best druggability 0.53
Structure
x-ray diffraction · 4 distinct chains · 35% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glycosylasparaginase (EC 3.5.1.26) | protein | 138 | 43% helix, 15% strand | Q47898 |
| B | Glycosylasparaginase (EC 3.5.1.26) | protein | 143 | 27% helix, 34% strand | Q47898 |
| C | Glycosylasparaginase (EC 3.5.1.26) | protein | 140 | 44% helix, 15% strand | Q47898 |
| D | Glycosylasparaginase (EC 3.5.1.26) | protein | 144 | 26% helix, 35% strand | Q47898 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 59 | 0.53 | 0.88 | 25 | empty |
| 2 | 143 | 0.46 | 0.77 | 30 | empty |
| 3 | 91 | 0.34 | 0.74 | 15 | empty |
| 4 | 83 | 0.34 | 0.75 | 18 | empty |
| 5 | 61 | 0.27 | 0.73 | 11 | empty |
Interfaces
6 interfaces between chains.
- A–B · 2687 Ų buried · 50 hydrogen bonds · protein-protein
- C–D · 2646 Ų buried · 46 hydrogen bonds · protein-protein
- A–D · 700 Ų buried · 11 hydrogen bonds · protein-protein
- B–C · 665 Ų buried · 9 hydrogen bonds · protein-protein
- B–D · 645 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q47898
- Elsewhere: RCSB PDB 1AYY · PDBe 1AYY · UniProt Q47898
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