UniProt Q47898
Protein (glycosylasparaginase) (Q47898)
Protein (glycosylasparaginase) (UniProt Q47898), EC 3.5.1.26: 22 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q47898
- Protein
- Protein (glycosylasparaginase)
- EC
- 3.5.1.26
- Experimental structures
- 22
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 16 · 3 records with a druggable one
Structures
23 records of Q47898 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AYY | Glycosylasparaginase | x-ray diffraction | A, B, C, D | — | — |
| 1AYY | Glycosylasparaginase | x-ray diffraction | A, B, C, D | — | — |
| 1P4K | Crystal structure of the glycosylasparaginase precursor D151N mutant | x-ray diffraction | A, C | — | — |
| 1P4K | Crystal structure of the glycosylasparaginase precursor D151N mutant | x-ray diffraction | A, C | — | — |
| 1P4V | Crystal structure of the glycosylasparaginase precursor D151N mutant with glycine | x-ray diffraction | A, C | — | — |
| 1P4V | Crystal structure of the glycosylasparaginase precursor D151N mutant with glycine | x-ray diffraction | A, C | — | — |
| 2GAC | T152C mutant glycosylasparaginase from flavobacterium meningosepticum | x-ray diffraction | A, B, C, D | — | — |
| 2GAC | T152C mutant glycosylasparaginase from flavobacterium meningosepticum | x-ray diffraction | A, B, C, D | — | — |
| 2GAW | Wild type glycosylasparaginase from flavobacterium meningosepticum | x-ray diffraction | A, B, C, D | — | — |
| 2GAW | Wild type glycosylasparaginase from flavobacterium meningosepticum | x-ray diffraction | A, B, C, D | — | — |
| 2GL9 | Crystal Structure of Glycosylasparaginase-Substrate Complex | x-ray diffraction | A, B, C, D | — | — |
| 2GL9 | Crystal structure of glycosylasparaginase-substrate complex | x-ray diffraction | A, B, C, D | — | — |
| 3LJQ | Crystal Structure of the Glycosylasparaginase T152C apo-precursor | x-ray diffraction | A, C | — | — |
| 3LJQ | Crystal structure of the glycosylasparaginase T152C apo-precursor | x-ray diffraction | A, C | — | — |
| 4R4Y | Structural basis of a point mutation that causes the genetic disease Aspartylglucosaminuria | x-ray diffraction | A, B | — | — |
| 4R4Y | Structural basis of a point mutation that causes the genetic disease aspartylglucosaminuria | x-ray diffraction | A, B | — | — |
| 9GAA | Precursor of the T152A mutant glycosylasparaginase from flavobacterium meningosepticum | x-ray diffraction | A, C | — | 6 (best 0.58) |
| 9GAA | Precursor of the T152A mutant glycosylasparaginase from flavobacterium meningosepticum | x-ray diffraction | A, C | — | — |
| 9GAC | Precursor of the T152C mutant glycosylasparaginase from flavobacterium meningosepticum | x-ray diffraction | A, C | GLY | 5 (best 0.57) |
| 9GAC | Precursor of the T152C mutant glycosylasparaginase from flavobacterium meningosepticum | x-ray diffraction | A, C | — | — |
| 9GAF | Precursor of the W11F mutant glycosylasparaginase from flavobacterium meningosepticum | x-ray diffraction | A, C | GLY | 5 (best 0.62) |
| 9GAF | Precursor of the W11F mutant glycosylasparaginase from flavobacterium meningosepticum | x-ray diffraction | A, C | — | — |
| Q47898 | AlphaFold monomer V2.0 prediction for N(4)-(beta-N- acetylglucosaminyl)-L-asparaginase (Q47898) | predicted | A | — | — |
Ligands
- GLY · Glycine · in 2 records
Experiment against prediction
- 1P4K chain C against the predicted model Q47898: TM-score 1.00, RMSD 0.24 Å
- 1P4K chain C against the predicted model Q47898: TM-score 1.00, RMSD 0.24 Å
- 9GAA chain C against the predicted model Q47898: TM-score 1.00, RMSD 0.31 Å
- 9GAA chain C against the predicted model Q47898: TM-score 1.00, RMSD 0.31 Å
- 1P4K chain A against the predicted model Q47898: TM-score 1.00, RMSD 0.35 Å
- 1P4K chain A against the predicted model Q47898: TM-score 1.00, RMSD 0.35 Å
- 9GAC chain C against the predicted model Q47898: TM-score 1.00, RMSD 0.39 Å
- 9GAC chain A against the predicted model Q47898: TM-score 1.00, RMSD 0.40 Å
- 1AYY chain A against the predicted model Q47898: TM-score 1.00, RMSD 0.30 Å
- 1AYY chain A against the predicted model Q47898: TM-score 1.00, RMSD 0.30 Å
Elsewhere
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