Research workbench

Firefly luciferase

Analyse Firefly luciferase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1LCI
Type: protein
Length: 523 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Luciferase
EC: 1.13.12.7
UniProt: P08659
Pockets: 4 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Luciferase (EC 1.13.12.7)	protein	523	33% helix, 24% strand	P08659

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	200	0.70	0.87	45	empty
2	201	0.49	0.76	35	empty
3	81	0.35	0.75	18	empty
4	52	0.27	0.74	15	empty

Compared structures

1LCI · Firefly luciferase · the same entry in another collection · chain A against A, TM-score 1.00
P08659 · AlphaFold monomer V2.0 prediction for luciferin 4-monooxygenase (P08659) · a predicted model of the same protein · chain A against A, TM-score 0.83

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08659
Elsewhere: RCSB PDB 1LCI · PDBe 1LCI · UniProt P08659

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