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Solution structure of calcium saturated cardiac troponin C in the troponin C-troponin I complex

Analyse Solution structure of calcium saturated cardiac troponin C in the troponin… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1LA0
Type: protein
Length: 161 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Troponin C, slow skeletal and cardiac muscles
UniProt: P09860
Ligands: CA
Pockets: 1 · best druggability 0.48

Structure

solution nmr · 1 distinct chain · 50% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Troponin C, slow skeletal and cardiac muscles	protein	161	50% helix, 1% strand	P09860

Ligands and binding sites

CA · Calcium ion · metal · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	75	0.48	0.82	23	empty

Compared structures

1LA0 · Solution Structure of Calcium Saturated Cardiac Troponin C in the Troponin C-Troponin I… · the same entry in another collection · chain A against A, TM-score 1.00
P09860 · AlphaFold monomer V2.0 prediction for troponin C, slow skeletal and cardiac muscles… · a predicted model of the same protein · chain A against A, TM-score 0.51

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P09860
Elsewhere: RCSB PDB 1LA0 · PDBe 1LA0 · UniProt P09860

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