Research workbench
Crystal structure of DNA cross-link repair protein 1A in complex with ceftriaxone (alternative site)
Analyse Crystal structure of DNA cross-link repair protein 1A in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5NZX
- Type
- protein
- Length
- 336 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA cross-link repair 1A protein
- UniProt
- Q6PJP8
- Ligands
- 9F2, NI
- Pockets
- 3 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 34% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA cross-link repair 1A protein | protein | 336 | 34% helix, 22% strand | Q6PJP8 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 242 | 0.60 | 0.80 | 41 | empty |
| 2 | 102 | 0.47 | 0.80 | 22 | empty |
| 3 | 94 | 0.34 | 0.74 | 17 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 5NZX · Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone… · the same entry in another collection · chain A against A, TM-score 1.00
- Q6PJP8 · AlphaFold monomer V2.0 prediction for DNA cross-link repair 1A protein (Q6PJP8) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6PJP8
- Elsewhere: RCSB PDB 5NZX · PDBe 5NZX · UniProt Q6PJP8
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