Research workbench
Crystal structure of the SEC7 domain of yeast GEA2
Analyse Crystal structure of the SEC7 domain of yeast GEA2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1KU1
- Type
- protein
- Length
- 422 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Arf guanine-nucleotide exchange factor 2
- UniProt
- P39993
- Pockets
- 3 · best druggability 0.45
Structure
x-ray diffraction · 1 distinct chain · 59% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Arf guanine-nucleotide exchange factor 2 | protein | 211 | 59% helix, 1% strand | P39993 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 158 | 0.45 | 0.75 | 23 | empty |
| 2 | 77 | 0.40 | 0.79 | 25 | empty |
| 3 | 54 | 0.27 | 0.74 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 976 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 1KU1 · Crystal Structure of the Sec7 Domain of Yeast GEA2 · the same entry in another collection · chain A against A, TM-score 1.00
- P39993 · AlphaFold monomer V2.0 prediction for arf guanine-nucleotide exchange factor 2 (P39993) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P39993
- Elsewhere: RCSB PDB 1KU1 · PDBe 1KU1 · UniProt P39993
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