UniProt P39993
ARF guanine-nucleotide exchange factor 2 (P39993)
ARF guanine-nucleotide exchange factor 2 (UniProt P39993): 4 experimental structures and 1 predicted model on GenesisL1, 39 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P39993
- Protein
- ARF guanine-nucleotide exchange factor 2
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 39 · 2 records with a druggable one
Structures
5 records of P39993 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1KU1 | Crystal Structure of the Sec7 Domain of Yeast GEA2 | x-ray diffraction | A, B | — | — |
| 1KU1 | Crystal structure of the SEC7 domain of yeast GEA2 | x-ray diffraction | A, B | — | — |
| 8EZJ | Cryo-EM structure of the S. cerevisiae Arf-like protein Arl1 bound to the Arf guanine nucleotide… | electron microscopy | A, B | — | 19 (best 0.83) |
| 8EZQ | Cryo-EM structure of the S. cerevisiae guanine nucleotide exchange factor Gea2 | electron microscopy | A, B | — | 20 (best 0.84) |
| P39993 | AlphaFold monomer V2.0 prediction for arf guanine-nucleotide exchange factor 2 (P39993) | predicted | A | — | — |
Experiment against prediction
- 8EZJ chain B against the predicted model P39993: TM-score 0.97, RMSD 2.00 Å
- 8EZQ chain B against the predicted model P39993: TM-score 0.97, RMSD 2.16 Å
- 8EZJ chain A against the predicted model P39993: TM-score 0.95, RMSD 2.66 Å
- 8EZQ chain A against the predicted model P39993: TM-score 0.95, RMSD 2.72 Å
- 1KU1 chain A against the predicted model P39993: TM-score 0.94, RMSD 1.58 Å
- 1KU1 chain A against the predicted model P39993: TM-score 0.94, RMSD 1.58 Å
- 1KU1 chain B against the predicted model P39993: TM-score 0.90, RMSD 1.99 Å
- 1KU1 chain B against the predicted model P39993: TM-score 0.90, RMSD 1.99 Å
Elsewhere
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