Research workbench

IgE-Fc in complex with single domain antibody 026

Analyse IgE-Fc in complex with single domain antibody 026 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5NQW
Type: protein
Length: 668 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P01854
Ligands: MAN, NAG, BMA

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	210	—	P01854
B	—	protein	212	—	P01854
C	—	protein	123	—	—
D	—	protein	123	—	—

Ligands and binding sites

MAN · alpha-D-mannopyranose · sugar · 8 copies · chains A, B
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A, B
BMA · beta-D-mannopyranose · sugar · 2 copies · chains A, B
GOL · Glycerol · additive · 2 copies · chains B, C, A, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5NQW · IgE-Fc in complex with single domain antibody 026 · the same entry in another collection · chain A against A, TM-score 1.00
P01854 · AlphaFold monomer V2.0 prediction for immunoglobulin heavy constant epsilon (P01854) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P01854
Elsewhere: RCSB PDB 5NQW · PDBe 5NQW · UniProt P01854

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