Crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium and the insti XZ407 (compound 5G)

Structure

x-ray diffraction · 4 distinct chains.

Ligands and binding sites

• XZ4 · Methyl 2-[[3-[[2,4-bis(fluoranyl) phenyl]methylcarbamoyl]-7-methoxy-1-oxidanyl-2-oxidanylidene-1,8-naphthyridin-4-yl]amino]ethanoate · ligand · chains A, C, D
• MG · Magnesium ion · metal · 3 copies · chains A, B
• ZN · Zinc ion · metal · chains A
• SO4 · Sulfate ion · ion · 8 copies · chains A, C, B, D
• GOL · Glycerol · additive · 6 copies · chains A, B, C, D
• MES · 2-(N-morpholino)-ethanesulfonic acid · additive · chains A, D
• HEZ · Hexane-1,6-diol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 5NO1 · Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P14350
• Elsewhere: RCSB PDB 5NO1 · PDBe 5NO1 · UniProt P14350