Research workbench
Structural basis of gene regulation by the grainyhead transcription factor superfamily
Analyse Structural basis of gene regulation by the grainyhead transcription factor… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5MPH
- Type
- protein
- Length
- 205 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Grainyhead-like protein 1 homolog
- UniProt
- Q9NZI5
- Ligands
- IOD
- Pockets
- 2 · best druggability 0.44
Structure
x-ray diffraction · 1 distinct chain · 13% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Grainyhead-like protein 1 homolog | protein | 205 | 13% helix, 37% strand | Q9NZI5 |
Ligands and binding sites
- IOD · Iodide ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 105 | 0.44 | 0.79 | 16 | empty |
| 2 | 50 | 0.29 | 0.76 | 16 | empty |
Compared structures
- 5MPH · Structural Basis of Gene Regulation by the Grainyhead Transcription Factor Superfamily · the same entry in another collection · chain A against A, TM-score 1.00
- Q9NZI5 · AlphaFold monomer V2.0 prediction for grainyhead-like protein 1 homolog (Q9NZI5) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NZI5
- Elsewhere: RCSB PDB 5MPH · PDBe 5MPH · UniProt Q9NZI5
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