Research workbench
Crystal structure of the kinetochore MIS12 complex HEAD2 subdomain containing DSN1 and NSL1 fragments
Analyse Crystal structure of the kinetochore MIS12 complex HEAD2 subdomain containing… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5LSI
- Type
- protein
- Length
- 158 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Kinetochore-associated protein DSN1 homolog; Kinetochore-associated protein NSL1 homolog
- UniProt
- Q9H410, Q96IY1
- Ligands
- SO4
Structure
x-ray diffraction · 2 distinct chains · 59% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| D | Kinetochore-associated protein DSN1 homolog | protein | 82 | 67% helix, 0% strand | Q9H410 |
| E | Kinetochore-associated protein NSL1 homolog | protein | 76 | 50% helix, 9% strand | Q96IY1 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- D–E · 1645 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
- 5LSI · Crystal structure of the kinetochore MIS12 complex HEAD2 subdomain containing DSN1 and… · the same entry in another collection · chain D against D, TM-score 1.00
- Q9H410 · AlphaFold monomer V2.0 prediction for kinetochore-associated protein DSN1 homolog (Q9H410) · a predicted model of the same protein · chain D against A, TM-score 0.96
- Q96IY1 · AlphaFold monomer V2.0 prediction for kinetochore-associated protein NSL1 homolog (Q96IY1) · a predicted model of the same protein · chain E against A, TM-score 0.82
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H410
- Every structure of UniProt Q96IY1
- Elsewhere: RCSB PDB 5LSI · PDBe 5LSI · UniProt Q9H410 · UniProt Q96IY1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.