UniProt Q96IY1
Kinetochore-associated protein NSL1 homolog (Q96IY1)
Kinetochore-associated protein NSL1 homolog (UniProt Q96IY1): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 37 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q96IY1
- Protein
- Kinetochore-associated protein NSL1 homolog
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 37 · 4 records with a druggable one
Structures
11 records of Q96IY1 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4NF9 | Structure of the Knl1/Nsl1 complex | x-ray diffraction | C, D | — | 1 (best 0.50) |
| 4NF9 | Structure of the KNL1/NSL1 complex | x-ray diffraction | C, D | — | — |
| 5LSI | Crystal structure of the kinetochore MIS12 complex HEAD2 subdomain containing DSN1 and NSL1… | x-ray diffraction | E | SO4 | — |
| 5LSI | Crystal structure of the kinetochore MIS12 complex HEAD2 subdomain containing DSN1 and NSL1… | x-ray diffraction | E | SO4 | — |
| 5LSJ | CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C delta-HEAD2 COMPLEX | x-ray diffraction | N, G | — | 9 (best 0.75) |
| 5LSJ | Crystal structure of the human kinetochore MIS12-cenp-C delta-HEAD2 complex | x-ray diffraction | N, G | — | — |
| 5LSK | Crystal structure of the human kinetochore MIS12-cenp-C complex | x-ray diffraction | N | — | 1 (best 0.67) |
| 5LSK | Crystal structure of the human kinetochore MIS12-cenp-C complex | x-ray diffraction | N | — | — |
| 8PPR | Structure of the human outer kinetochore KMN network complex | electron microscopy | N | — | 10 (best 0.64) |
| 8Q5H | Human KMN network (outer kinetochore) | electron microscopy | N | — | 16 (best 0.85) |
| Q96IY1 | AlphaFold monomer V2.0 prediction for kinetochore-associated protein NSL1 homolog (Q96IY1) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 5LSI chain E against the predicted model Q96IY1: TM-score 0.82, RMSD 1.53 Å
- 5LSI chain E against the predicted model Q96IY1: TM-score 0.82, RMSD 1.53 Å
- 4NF9 chain C against the predicted model Q96IY1: TM-score 0.53, RMSD 0.75 Å
- 4NF9 chain C against the predicted model Q96IY1: TM-score 0.53, RMSD 0.75 Å
- 5LSJ chain N against the predicted model Q96IY1: TM-score 0.47, RMSD 2.24 Å
- 5LSJ chain N against the predicted model Q96IY1: TM-score 0.47, RMSD 2.24 Å
- 5LSJ chain G against the predicted model Q96IY1: TM-score 0.47, RMSD 2.40 Å
- 5LSJ chain G against the predicted model Q96IY1: TM-score 0.47, RMSD 2.40 Å
- 5LSK chain N against the predicted model Q96IY1: TM-score 0.45, RMSD 4.44 Å
- 5LSK chain N against the predicted model Q96IY1: TM-score 0.45, RMSD 4.44 Å
Elsewhere
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