Research workbench
Crystal structure of the WSS1 E203Q mutant from S. pombe
Analyse Crystal structure of the WSS1 E203Q mutant from S. pombe in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5LN5
- Type
- protein
- Length
- 225 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ubiquitin and wlm domain-containing metalloprotease SPCC1442.07C
- EC
- 3.4.24.-
- UniProt
- O94580
- Ligands
- NI, CO3
- Pockets
- 1 · best druggability 0.63
Structure
x-ray diffraction · 2 distinct chains · 43% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ubiquitin and wlm domain-containing metalloprotease SPCC1442.07C (EC 3.4.24.-) | protein | 113 | 43% helix, 20% strand | O94580 |
| B | Ubiquitin and wlm domain-containing metalloprotease SPCC1442.07C (EC 3.4.24.-) | protein | 112 | 43% helix, 19% strand | O94580 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 450 | 0.63 | 0.77 | 40 | empty |
Interfaces
1 interface between chains.
- A–B · 132 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 5LN5 · Crystal structure of the Wss1 E203Q mutant from S. pombe · the same entry in another collection · chain B against B, TM-score 1.00
- O94580 · AlphaFold monomer V2.0 prediction for DNA-dependent metalloprotease WSS1 homolog 2… · a predicted model of the same protein · chain B against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O94580
- Elsewhere: RCSB PDB 5LN5 · PDBe 5LN5 · UniProt O94580
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