Research workbench
Vibrio cholerae neuraminidase
Analyse Vibrio cholerae neuraminidase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1KIT
- Type
- protein
- Length
- 757 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sialidase
- EC
- 3.2.1.18
- UniProt
- P37060
- Ligands
- CA
- Pockets
- 6 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 6% helix, 51% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sialidase (EC 3.2.1.18) | protein | 757 | 6% helix, 51% strand | P37060 |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 426 | 0.69 | 0.81 | 65 | empty |
| 2 | 144 | 0.61 | 0.85 | 24 | empty |
| 3 | 233 | 0.60 | 0.80 | 26 | empty |
| 4 | 109 | 0.42 | 0.76 | 20 | empty |
| 5 | 113 | 0.36 | 0.74 | 23 | empty |
Compared structures
- 1KIT · Vibrio cholerae neuraminidase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P37060
- Elsewhere: RCSB PDB 1KIT · PDBe 1KIT · UniProt P37060
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