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Co-crystal structure of PKA ri alpha cnb-B domain with camp

Analyse Co-crystal structure of PKA ri alpha cnb-B domain with camp in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5KJX
Type: protein
Length: 141 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Camp-dependent protein kinase type I-alpha regulatory subunit
UniProt: P10644
Ligands: CMP
Pockets: 1 · best druggability 0.65

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Camp-dependent protein kinase type I-alpha regulatory subunit	protein	141	31% helix, 31% strand	P10644

Ligands and binding sites

CMP · Adenosine-3',5'-cyclic-monophosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	151	0.65	0.86	24	CMP

Compared structures

5KJX · Co-crystal Structure of PKA RI alpha CNB-B domain with cAMP · the same entry in another collection · chain A against A, TM-score 1.00
P10644 · AlphaFold monomer V2.0 prediction for camp-dependent protein kinase type I-alpha… · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P10644
Elsewhere: RCSB PDB 5KJX · PDBe 5KJX · UniProt P10644

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