UniProt P10644
cAMP-dependent protein kinase type I-alpha regulatory subunit (P10644)
cAMP-dependent protein kinase type I-alpha regulatory subunit (UniProt P10644): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 2 pockets. Binding sites, druggability and experiment against…
- UniProt
- P10644
- Protein
- cAMP-dependent protein kinase type I-alpha regulatory subunit
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 2 · 2 records with a druggable one
Structures
7 records of P10644 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5KJX | Co-crystal Structure of PKA RI alpha CNB-B domain with cAMP | x-ray diffraction | A | CMP | 1 (best 0.65) |
| 5KJX | Co-crystal structure of PKA ri alpha cnb-B domain with camp | x-ray diffraction | A | CMP | — |
| 5KJY | Co-crystal structure of PKA RI alpha CNB-B mutant (G316R/A336T) with cAMP | x-ray diffraction | A | CMP | — |
| 5KJY | Co-crystal structure of PKA ri alpha cnb-B mutant (G316R/A336T) with camp | x-ray diffraction | A | CMP | — |
| 5KJZ | Co-crystal structure of PKA RI alpha CNB-B mutant (G316R/A336T) with cGMP | x-ray diffraction | A | PCG | 1 (best 0.66) |
| 5KJZ | Co-crystal structure of PKA ri alpha cnb-B mutant (G316R/A336T) with cgmp | x-ray diffraction | A | PCG | — |
| P10644 | AlphaFold monomer V2.0 prediction for camp-dependent protein kinase type I-alpha regulatory subunit… | predicted | A | — | — |
Ligands
Experiment against prediction
- 5KJY chain A against the predicted model P10644: TM-score 0.95, RMSD 1.01 Å
- 5KJY chain A against the predicted model P10644: TM-score 0.95, RMSD 1.01 Å
- 5KJX chain A against the predicted model P10644: TM-score 0.94, RMSD 0.92 Å
- 5KJX chain A against the predicted model P10644: TM-score 0.94, RMSD 0.92 Å
- 5KJZ chain A against the predicted model P10644: TM-score 0.88, RMSD 2.21 Å
- 5KJZ chain A against the predicted model P10644: TM-score 0.88, RMSD 2.21 Å
Elsewhere
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